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as present the greater part of the time.

* * * * *

From the foregoing, and from additional experiments, which it is not necessary to give in detail, it appeared, that when applied to a wound made in the most sensitive parts of the integuments, the oil of tobacco, though it caused a good deal of pain, had a far less general effect than when applied to the tongue. Rats were less affected than cats. Two and sometimes three drops rubbed upon the tongue of a rat, did not kill in half an hour.

Three large drops rubbed upon the tongue of a full-sized cat, usually caused death in from three to ten minutes, and in one instance, already stated, in two minutes and forty-five seconds. One drop passed into the jugular vein of a large dog, occasioned an immediate cry, followed in a few moments by staggering, convulsive twitchings of the voluntary muscles, and vomiting.

In those cases in which full vomiting occurred, evident relief fo

as present the greater part of the time.

* * * * *

From the foregoing, and from additional experiments, which it is not necessary to give in detail, it appeared, that when applied to a wound made in the most sensitive parts of the integuments, the oil of tobacco, though it caused a good deal of pain, had a far less general effect than when applied to the tongue. Rats were less affected than cats. Two and sometimes three drops rubbed upon the tongue of a rat, did not kill in half an hour.

Three large drops rubbed upon the tongue of a full-sized cat, usually caused death in from three to ten minutes, and in one instance, already stated, in two minutes and forty-five seconds. One drop passed into the jugular vein of a large dog, occasioned an immediate cry, followed in a few moments by staggering, convulsive twitchings of the voluntary muscles, and vomiting.

In those cases in which full vomiting occurred, evident relief fo